Get Breaking News Delivered to Your Inbox Study participants were given a reduced-calorie diet and an increased exercise regimen, along with either Saxenda or a placebo. Those who took Saxenda lost an average of 18 and a half pounds over 56 weeks. Those taking a placebo only lost 6 pounds.

In clinical trials, Saxenda was found to result in a small drop in systolic blood pressure (the top number) of approximately 2.8 millimeters of mercury. However, treatment with Saxenda was also shown to be associated with an increase in heart rate of 3 beats per minute.

Saxenda approval included an assumption that patients would correct their lifestyles. If they do not improve diet or increase physical activity, the effect of the weight loss will diminish, Park said. In such a case, discontinuing Saxenda would make patients gain weight again, she added.

Saxenda is an injectable medication you take once a day. You may inject it at the most convenient time for you (e.g., before breakfast, lunch, dinner, or bedtime), but it should be taken at approximately the same time each day.

The newly approved drugs — Belviq, Qsymia, Contrave and Saxenda — work by suppressing appetite, among other things. Saxenda is administered via subcutaneous injection; the other three drugs come in pill form.

Saxenda® may help some adults with excess weight (BMI of greater than 27 to 29.9) who also have weight-related medical problems or obesity, BMI of greater than or equal to 30, to lose weight and keep it off.

At least 100 of those reported deaths were linked to pancreatic cancer. Clinical trials for both Victoza and Saxenda raised concerns – still unresolved – that both drugs may increase the risk of pancreatitis, which can increase the risk of pancreatic cancer.

Ozempic (semaglutide) Injection and Saxenda, Victoza (liraglutide [rDNA origin]) Injection are glucagon-like peptide 1 (GLP-1) receptor agonists indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

When you first start Saxenda, a single pen will last 17 days and the first full pack of five pens will last six weeks. When you take Saxenda you need to gradually increase your dose in 0.6mg intervals, until you reach what is called the maintenance dose at 3mg daily.

Study participants were given a reduced-calorie diet and an increased exercise regimen, along with either Saxenda or a placebo. Those who took Saxenda lost an average of 18 and a half pounds over 56 weeks.